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1.
Indian J Pathol Microbiol ; 2022 Jun; 65(2): 396-400
Article | IMSEAR | ID: sea-223239

ABSTRACT

Carcinoma cervix usually spreads directly to contiguous structures, such as the vagina, urinary bladder, ureter, and rectum. Intestinal metastasis from cervical cancer is very uncommon and accounts for less than 4% of cases and to date, 24 cases have been reported in Medical literature. These may be asymptomatic or present with features of intestinal obstruction, bowel wall perforation, and mimic acute abdomen. Intestinal metastasis is a late occurrence and carries a poor prognosis, hence a high index of suspicion with prompt diagnosis and management is essential. We report a series of five patients with squamous cell carcinoma (SCC) of the cervix with intestinal metastasis diagnosed in our hospital.

2.
Acta Academiae Medicinae Sinicae ; (6): 294-298, 2022.
Article in Chinese | WPRIM | ID: wpr-927878

ABSTRACT

Mucins,a family of heavily glycosylated proteins,present mainly in epithelial cells.They function as essential barriers for epithelium and play important roles in cellular physiological processes.Aberrant expression and glycosylation of mucins in gastric epithelium occur at pathological conditions,such as Helicobacter pylori infection,chronic atrophic gastritis,intestinal metastasis,dysplasia,and gastric cancer.This review addresses the major roles played by mucins and associated O-glycan structures in normal gastric epithelium.Further,we expound the alterations of expression patterns and glycan signatures of mucins at those pathological conditions.


Subject(s)
Humans , Gastric Mucosa/pathology , Glycosylation , Helicobacter Infections/pathology , Helicobacter pylori/metabolism , Mucins/metabolism , Stomach Neoplasms/pathology
4.
Korean Journal of Gastrointestinal Endoscopy ; : 947-950, 2000.
Article in Korean | WPRIM | ID: wpr-86215

ABSTRACT

Lung cancer begins insidiously, metastasizes early, and is frequently nonresectable at the time of diagnosis. Gastrointestinal metastases are considered the most unusual. A 60 year-old man was admitted for the evaluation of dizziness. For two weeks prior to admission, he had mild blood-tinged sputum and melena. He had right cervical lymphadenopathy, measured by 2 2 cm. Laboratory studies demonstrated hemoglobin of 3.7 g/dL. Posteroanterior and lateral chest radiographs revealed mass-like lesion of right upper lobe. An umblicated mass was found in the sigmoid colon by colonoscopic examination and biopsy was done. He developed abdominal pain, tenderness and rebound tenderness at admission 10 days. Abdominal CT showed that focal thickened wall and suspicious perforated lesion at the ileum. Operation was done. In recent time, we experienced a case in which perforation of gastrointestinal metastases developed with malignant tumors of the lung.


Subject(s)
Humans , Middle Aged , Abdominal Pain , Biopsy , Colon, Sigmoid , Diagnosis , Dizziness , Ileum , Lung Neoplasms , Lung , Lymphatic Diseases , Melena , Neoplasm Metastasis , Radiography, Thoracic , Sputum , Tomography, X-Ray Computed
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